Full activation of the skin barrier with Sage active cells

Serene Skin Sage​ is made of whole plant cells of sage (salvia officinalis), a famous European medicinal and fragrant species, used in tradictional medicines since Antiquity that will enhance the skin barrier function.

Fortress skin​

As the epidermis contains different types of defense systems, Serene Skin Sage​ boosts three aspects of the skin barrier: the physical barrier, by reinforcing the corneous layer; the chemical barrier by rebalancing the antimicrobial arsenal, and the immune-modulatory barrier by reducing pro-inflammatory cytokines. Therefore It provides the following effects on the epidermis:

Regenerating and restructuring: through increased cell renewal – increased KI67, loricrin and synthesis of lipids (ceramides and free fatty acids)

Protective: due to increased expression of three anti-microbial peptides (LL-37, Betadefensin 2 and psoriasin)

Balancing: through regulation of the microbial balance in the skin microbiota

Soothing: thanks to a decrease in TNF-alpha and IL1 alpha

As a result, a clinical study carried out on 20 women from 20 to 65 years-old showed an overall improvement in skin tone in terms of radiance (+30%), homogeneity (+21%) and redness (-26%), after 28 days of treatment (two applications a day).

Serene Skin Sage​ is not allergenic, preservative free, and can be used in any type of formulation from skincare  - daycreams, daily treatments, essence and serums, masks, etc. -  to make-up applications  - foundation, primer, BB creams, eye contour, pressed powder, etc.) in any type of formulation, liquid or solid.

Serene Skin Sage​ suits any type of skin, especially mature skins.

Cosmos Natural approvals and ISO 16128 certificates for all liquid forms available on request.